With the spread of the pandemic we face new challenges throughout the world but also in Croatia, resulting in novelties concerning the composition and activity of physical medicine and rehabilitation. Numerous experts are dealing with the rehabilitation of COVID-19 patients including physiotherapists, the latter aren’t included in the treatment of the disease but rather in the prevention of the usage of respiratory equipment and the functional shortage of daily activities. Physiotherapists are included in the rehabilitation and the acute state of the disease, especially in those cases when breathing has been aggravated due to post-viral fatigue. Early evaluation and intervention in the health of a COVID-19 patient are very important for prohibiting the further progress of the disease in order to decrease the risk of severe disability after recovery. In a mild case of the disease the patients don’t have any symptoms or experience symptoms like a fever, eye weakness, myalgia, a cough, etc. Those symptoms don’t require hospitalization. In severe cases of the disease the present numerous symptoms are given and the patients have a higher risk of continued complications, therefore it’s required to hospitalize those patients under constant supervision. The duty of health institutes is to secure adequate hygienic equipment in all clinical areas.