Exercise is an effective therapy in reducing emotional, mental and psychological changes in neurological patients. Aerobic exercises have been shown to be the most effective in reducing depression and anxiety in all neurological diseases. Other types of exercise were resistance exercises, balance exercises, proprioception exercises, stretching exercises and hippotherapy. Of the alternative methods, Asian medical practices, such as Qigong and Tai Chi, as well as yoga, have proven to be the most common. In the case of some neurological diseases, it has been shown that exercise is better performed with music. Therefore, dance proved to be an effective therapy in reducing neurobehavioral symptoms. Likewise, in most cases, the implementation of aerobic exercises has been shown to be effective if performed in water. Symptoms other than depression and anxiety that exercise was effective on were aggressiveness, irritability, tension, confusion, delirium, emotional instability and others. The duration, intensity and frequency of exercise depended on the impact of exercise. The recommended usual intensity was moderate and the recommendation is that the exercise should be held for 60 minutes 3 times a week. For long-term results, it was enough to exercise for 12 weeks, except for brain tumor survivors who required more time to adapt to exercise and at the same time, to achieve positive results in reducing emotional, mental and psychological changes.