Tumor diagnosis is becoming more frequent today. In terms of mortality, tumors are among the leading diseases of the modern world. Physiotherapy is the main component of the rehabilitation process, therefore it is necessary to acquire new skills, follow innovations in technology and science and contribute to creativity. Unfortunately, rehabilitation in oncology is not sufficiently represented in everyday practice. Treatment of patients with malignant diseases is a long and complex process and requires a multidisciplinary approach. A physiotherapist is an indispensable member of the team in the treatment of pediatric oncology patients who, through physiotherapy procedures, helps to restore the patient's function and improve the quality of his life. Physiotherapy intervention includes the implementation of therapeutic exercises and techniques and the resolution of tiredness and fatigue in activities of daily life. In oncology rehabilitation the physiotherapist starts working already in the intensive care unit. The physiotherapist has an important role because he prepares the child to resume a normal life. The goal is to enable the child to return to his activities, to be able to go to school, play with his peers, etc. During rehabilitation, the physiotherapist must be very creative when designing the rehabilitation program.