Manual therapy is a physical therapy technique that is performed by manual manipulation of the body to improve the functionality of the musculoskeletal system. It is used in rehabilitation after injuries, surgeries, sports injuries, back pain, migraines, problems with joints, muscles and other parts of the body. Mobilization techniques require the active participation of the patient, both in performing passive movements and in a combination of passive and active movements. There is a wide range of methods and approaches to manual therapy, such as Kaltenborn, Cyriax, Mulligan, Maitland and others. Cyriax's technique includes the application of transverse friction on soft tissues, joint traction, manipulation and mobilization. Mulligan's concept is based on transverse sliding between the spinous processes, combined with active movements of the spine, as well as specific techniques for peripheral joints. Maitland's approach involves a system of diagnosis and the application of mobilizations and manipulations. Kaltenborn's approach also includes assessment, mobilization and manipulation of the joint. The basis of treatment with the Mulligan method is a combination of passive mobilization of the joint with active movements. The aim of this paper is to show how manual therapy techniques affect the patient's painful conditions.