Spinal pain syndromes are divided into vertebral and vertebrogenic spinal syndromes. Vertebral pain syndromes are associated with pain and symptoms that occur in the cervical, thoracic, and lumbar spine. Vertebrogenic pain syndromes are associated with pain that can spread to the extremities (arms, legs) or head. There are cervical, cervicocephalic, cervicobrachial, thoracic and lumbar syndromes, as well as sciatica. Physiotherapy assessment begins with a subjective assessment, after which measurements and tests are performed, and finally the diagnosis, goals, and treatment plan are set. Considering the patient's clinical status, age, needs and desires, as well as their work and living environment, the patient goes through the stages of rehabilitation according to an individual approach. The purpose of writing this final paper is to define and identify the spinal pain syndromes, to explain their clinical picture, diagnosis, and treatment. To explain how physiotherapy assessment is performed and what procedures a physiotherapy intervention would cover. The aim is also to explain what quality of life is and to prove based on research that physiotherapy has a beneficial effect on improving the quality of life of people who have spinal pain syndromes.