There are many harmful effects of long rest. Prolonged lying down may cause complications for the patient, so they can become an even bigger problem than the primary disease itself, they can slow down or even prevent recovery. Complications of prolonged lying include decubitus, respiratory complications, deep vein thrombosis, joint contractures and muscle atrophy. Decubitus, damage to the skin and soft tissue, occurs as a result of longterm pressure on the skin. Respiratory complications occur very often in people who are in bed for a long period of time, so long-term bed rest is considered as a risk of lung infections. Deep vein thrombosis is characterized by the appearance of a clot, or thrombus in the deep veins of the legs, so the risk of pulmonary embolism, or venous thromboembolism, is significantly increased. As a result of physical inactivity and mechanical stress, there is a loss of muscle mass and strength, i.e. muscle atrophy. Over the period of time, the mobility of the joints decreases, which, consequently, leads to contractures. All the complications of longterm lying down listed above can be predicted and prevented. The prevention process differs between patients. Walking is the most important one. If that is not possible, patient should change his/her lying position, perform simple exercises and maintain hygiene.