Introduction: Physical activity is an integral part of preserving and improving the health status of young people. Technological progress leads to reduced physical activity which can consequently have a worrying health status. The aim of this research was to check how physically active of the students of the Osijek High School of Medicine are, and to check the satisfaction of the students with their own health and to what extent health or emotional problems disturb them in their everyday life. Methods: The research was conducted with the help of a survey questionnaire "Questionnaire on physical activity and certain health factors", which included the International Physical Activity Questionnaire (IPAQ - long form) and the health status questionnaire (SF-36). Results: 178 respondents participated in the research, 16% (N=29) male students and 83% (N=149) female students. The results of the IPAQ questionnaire showed that male students ride bicycles for more minutes per week, spend more minutes during the week performing extremely strenuous physical activity around the house, i.e. in the garden and yard, and engage in significantly more strenuous activities in their free time compared to female students. Female students spend significantly more time engaged in moderate activities inside the home. The results of the SF-36 questionnaire show that male students have more energy and are more vital and have better social functioning than female students. Discussion: The way of life and the use of free time is the reason for the decrease in activity. Physical inactivity can lead to the development of obesity, cardiovascular diseases, type II diabetes, malignant diseases, and the development of depression and anxiety. Conclusion: Prevention of physical inactivity and related health risks involves a conscious effort to include physical activity in daily life, which can be achieved through well-structured prevention programs.