Autophagy is a fundamental cell survival mechanism that enables cells to adapt to metabolic stress through the degradation and recycling of intracellular components, to generate macromolecular precursors and produce energy. Regular physical exercise becomes a non-pharmacological remedy for reducing cardiovascular morbidity and mortality due to exercise-induced benefits. Numerous studies have provided evidence that autophagy is activated in skeletal muscle in response to exercise. Exercise-induced regulation of autophagy involves both increased autophagy flux as well as transcriptional activation of important autophagy genes that can potentially lead to enhanced autophagy capacity. In addition to the literature review, research was conducted with the aim of finding out how familiar the general population is with the concept of autophagy and intermittent fasting, and what attitudes the general population has about autophagy and intermittent fasting. For research purposes, an online questionnaire was created and administered through social networks. Statistical processing was done with the help of the IBM Statistics SPSS 22 software. Although many are not familiar with the same term and the way of implementation, those who are, in the vast majority find positive effects in autophagy. Of course, there are those who consider autophagy negative. Through the conducted research, it can be concluded that among the respondents there were more of those with a positive experience and those who, based on this, recommend the inclusion of autophagy in everyday life.