The skeleton of the foot is divided into three parts; the hindfoot, the midfoot and the forefoot. The root of the foot makes 7 bones, forefoot contains five toes (phalanges) and five long bones (metatarsals). The metatarsal bones are tubular and there are five of them. Morton's neuroma is the most common cause of neuralgia in the foot. Morton's neuroma was first described by Thomas G. Morton in 1867. Morton's neuroma is a painful condition that affects the ball of your foot, most commonly the area between your third and fourth toes. Pain occurs in the front of the foot, especially during activity. Morton's neuroma can affect anyone and not just athletes. It affects middle-aged women because of the sensitivity and flexible nature of their feet. Another name for Morton's neuroma is metatarsalgia. Morton's neuroma involves a thickening of the tissue around one of the nerves leading to your toes. This can cause a sharp, burning pain in the ball of your foot. Morton's neuroma seems to occur in response to irritation, pressure or injury to one of the nerves that lead to your toes. Treatment can be conservative and surgical. Conservative approaches are more likely to be recommended by your doctor; it includes a medication, a physical therapy, a kinesitherapy or a custom-made, individually designed shoe insert. The corticosteroid injections are often used along with the exercise, the proper footwear and the medication. When performing kinesitherapy, it is very important to pay attention to the pain, the trophies, the deformities, the mobility and the way of walking. When performing exercises, attention should be given to the onset of pain. If the pain increases and the muscle spasm occur, it is a sign that the exercises are too strong. Kinesitherapy is never performed alone. It is performed in combination with the physical procedures. Surgical treatment is recommended only if the conservative treatment is not successful. The aim of the paperwork is to present what Morton's neuroma is, how to recognize it, what are possible prevention, treatment and rehabilitation and how the disease affects the quality of life.