Cystic fibrosis (mukoviszidose) is progressive hereditary didease which causes permanent lung infections and limits ability to breathe. Cystic fibrosis is most frequently diagnosed within a first year because symtoms appear in the early stage of life. Symptoms and sings of cystic fibrosis can vary dependingof on the progress of the disease. As the time passes, symptoms can get worse or better. The man risk factor that causes cystic fibrosis is that both parents are carriers of CFTR gene mutation. However, there are more factors that affect occurrence of cystic fibrosis. Treatment of cystic fibrosis lasts during the whole life, it requires persistence, optimism, patience from the patient, his family and doctor, that way the quality of life can be improved and the liftime of the patient can be extended. It is important to motivate and encourage patients participation in planning and conducting physiotherapeutic procedures, to be independent. Giving positive, verbal informations about his achievements will enable the patient to free himself from a sense of helplessness and low self esteem. Physiotherapy intervention mostly relates on testing lung function, techniques of cleaning respiratory tract, breathing techniques, even various forms of physical activity. Physiotherapy can affect better treatment and resistance, which is important for the quality of life in patients. With physiotherapy procedures, we try to give patients as normal life as possible. Treatmens are focused on healing the respiratory tract, improving lung ventilation, strengthening inspirational musculature.