Physical activity and recreational sport are related to different aspects of quality of life, and except physical health benefit, physical activity has a significant impact on the emotional and social health of the person as well. Handball is characterized by high intensity, frequent physical contact and sudden changes in the direction of movement used as a trick to achieve goal and therefore it is almost impossible to avoid sports injuries. The number of injured players is constantly increasing, especially at the professional level. Handball is a sport where the most common injuries are those of joints, muscles and tendons. When it comes to pain and injuries in sports, we most commonly refer to injuries to the locomotor system which make up to 80% of all sports injuries. Among the most common injuries to the lower extremities are the sprained ankle, and to the same or a slightly greater extent, injuries to the anterior cruciate ligament. Treatment includes resting and physical therapy, local use of anti-inflammatory medicine and in the most severe cases surgical treatment is applied. The main aim of the graduate thesis was to determine the specific sports injuries that occur in handball, which is the most common localization of sports injuries, whether the handball players had muscle, ligament and nerve injuries, what was the stage at the time of injury, how long was the recovery after the injury and whether physical therapy had been applied. The research part of the work was carried out with the help of a survey questionnaire which collected information on specific handball injuries.